Chemical Properties of Cyanide and Isocyanide Preparation and Properties

Chemical Properties of Cyanide and Isocyanide Preparation and Properties

→ Hydrolysis : On partial hydrolysis in basic and acidic medium, alkyl cyanides form amides. On complete hydrolysis amides give carboxylic acid in acidic medium and carboxylic acid salt in basic medium.

Chemical Properties of Cyanide and Isocyanide Preparation and Properties 1

→ Alkyl isocyanide on complete hydrolysis in acidic medium form primary amine and formic acid.

Chemical Properties of Cyanide and Isocyanide Preparation and Properties 2

→ Reduction : Alkyl halide on reduction in the presence of LiAlH4 or sodium and ethyl alcohol forms primary amine, this is called Mendius reduction.

Chemical Properties of Cyanide and Isocyanide Preparation and Properties 3

→ In opposite of it alkyl isocyanide on hydrogenation in presence of Pt or Ni forms secondary amines.

Chemical Properties of Cyanide and Isocyanide Preparation and Properties 4

→ Thorpe Reaction : In the presence of sodium catalyst in dry ether medium, two molecules of alkyl cyanide condenses to form dimer which is a member of imino cyanide family.

Chemical Properties of Cyanide and Isocyanide Preparation and Properties 5

→ From Grigriard’s Reagents : Grignard reagents added to nitrile giving intermediate imine salts which upon hydrolysis give ketones.

Chemical Properties of Cyanide and Isocyanide Preparation and Properties 6

→ Addition Reactions Alkyl isocyanide form addition compound with halogen, sulphur, ozone, mercuric oxide etc.

Chemical Properties of Cyanide and Isocyanide Preparation and Properties 7

→ Isomerisaton Alkyl isocyanide when heated strongly for a long time is converted to more stable cyanide.

Chemical Properties of Cyanide and Isocyanide Preparation and Properties 8

Chemistry Notes

Leave a Comment